Hi & Welcome. Incomplete data like age, gender, purpose of taking these medications, etc?? Based on the given history and the list of medications you seem to be suffering from hyperkalemia (increased level of potassium in the blood). When taken together the medications like Prinvil (Lisinopril) which is an angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure and potassium can increase the levels of potassium in your blood resulting in leg cramps. It may also cause fatigue, weakness and irregular heart beats, Quinine is not effective in the treatment of such condition, it was previously used to treat and prevent night leg cramps in adults and the elderly when sleep is regularly disrupted. However, due to its potential for serious and life-threatening adverse effects, it is no longer recommended as a treatment option. Consult your treating doctor as you may need a dose adjustment of these medications or to discontinue taking potassium. Meanwhile you should avoid taking potassium-rich foods such as tomatoes, raisins, figs, potatoes, beans, bananas, papayas, pears, and mangoes. Hope I could answer your queries. Best of your health. A feedback is appreciated.