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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Low Pulse Rate And Drowsiness While On Tizanidine?

I am taking tizanidine - 4mg and tramadol - 25mg....both twice a day. Symptoms of low pulse, sleepiness. From reading,this is a bad mix. Thus I want to stop taking the tizanidine but I understand that stopping completely and immediately is not recommended. Can I cut tizanidine in half or can I go to 2mg once a day at night ?
Thu, 10 May 2018
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General & Family Physician,  's  Response
Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.

Yes, Tizanidine can cause drowsiness. Stopping Tizanidine is not a big issue, you didn't mention for what purposes you are using it. What I understand that there is no problem in stopping it immediately if your disease itself is controlled without it.

So, I would advise that you can reduce the dose, better to take it in 2 mg two times because it won't work the whole day if taken once a day. If your primary problem for which you are taking the drug does not worsen a lot and you can stop it completely any time. However, this must be done with consultation of your primary doctor.

Hope I have answered your query. Let me know if I can assist you further.

Regards,      
Dr. Mahboob Ur Rahman
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What Causes Low Pulse Rate And Drowsiness While On Tizanidine?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Yes, Tizanidine can cause drowsiness. Stopping Tizanidine is not a big issue, you didn t mention for what purposes you are using it. What I understand that there is no problem in stopping it immediately if your disease itself is controlled without it. So, I would advise that you can reduce the dose, better to take it in 2 mg two times because it won t work the whole day if taken once a day. If your primary problem for which you are taking the drug does not worsen a lot and you can stop it completely any time. However, this must be done with consultation of your primary doctor. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Mahboob Ur Rahman