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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Nausea And Vomiting While Taking Rituxan For Non-hodgkin S Lymphoma?

My third chemo treatment for non-hodgskins lymphoma was Thursday May 1, 2015. I am given Retuxan each time without any ill effects. This morning (May 3, 2015) I woke up to nausea which led to vomiting. Its now 12:00 noon and I m still nauseated and vomiting. The only liquid I ve had was a few sip of water an hour ago. Should I be drinking more liquid?Judy
Sat, 26 Nov 2022
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Anesthesiologist 's  Response
Hello,

Rituxan is a monoclonal antibody and it's adverse effects are:
Angioedema (11%)
Asthenia (26%), chills (33%), dizziness (10%), fever (53%), headache (19%)
Pruritus (14%), rash (15%)
Abdominal pain (14%), diarrhea (10%), nausea (23%), vomiting (10%)
Leukopenia (14%), lymphopenia (48%), neutropenia (14%), thrombocytopenia (12%)
Back pain (10%), myalgia (10%)
Cough (13%), rhinitis (12%)
Infection (31%), night sweats (15%)
So, nausea is seen in 23% of patients taking the drug for Non-Hodgkin's lymphoma.

You can have ondansetron 4 mg tablet daily twice or thrice to prevent vomiting and treat nausea. You need to stay hydrated and electrolytes lost in vomiting must be replenished. If the vomiting and nausea do not come down with above treatment, please consult your treating physician.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Pallavi M., Anesthesiologist
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What Causes Nausea And Vomiting While Taking Rituxan For Non-hodgkin S Lymphoma?

Hello, Rituxan is a monoclonal antibody and it s adverse effects are: Angioedema (11%) Asthenia (26%), chills (33%), dizziness (10%), fever (53%), headache (19%) Pruritus (14%), rash (15%) Abdominal pain (14%), diarrhea (10%), nausea (23%), vomiting (10%) Leukopenia (14%), lymphopenia (48%), neutropenia (14%), thrombocytopenia (12%) Back pain (10%), myalgia (10%) Cough (13%), rhinitis (12%) Infection (31%), night sweats (15%) So, nausea is seen in 23% of patients taking the drug for Non-Hodgkin s lymphoma. You can have ondansetron 4 mg tablet daily twice or thrice to prevent vomiting and treat nausea. You need to stay hydrated and electrolytes lost in vomiting must be replenished. If the vomiting and nausea do not come down with above treatment, please consult your treating physician. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Pallavi M., Anesthesiologist