I have a pain/pressure in the middle of my chest when I m breathing hard. For example, strenuous exercise, hiking at altitude, and sometimes even short jogs. I m not over weight, I don t smoke, I eat well and am somewhat active. I have wine or beer once/day, usually. I m female, 49 and a formerl marathoner and triathlete. I haven t exercised regularly though since I had my son 6.5 years ago.