Hi, congratulations for your pregnancy. I can understand your concern related to your pregnancy. Hope you don t mind asking you if you have taken your Gynaecologist s advice before stopping Duphastone tablet. Generally after first trimester if there are no spotting and ultrasound abdomen shows normal report, continuing Duphastone in second trimester is not necessary and Duphastone doesn t cause any side effects after stopping the tablet. Coming to your query, lower back pain, lower abdominal pain, frequency urination, fatigue, anxiety, breathlessness, changes in the breast, secretion from nipple are common symptoms in second and third trimester of pregnancy. Though the symptoms differ from one individual to another, but due to constant hormonal and physiological changes in your body, you will experience lot of physical as well as emotional changes. There is nothing to worry, there are certain things you can do to reduce the back pain are: 1. Take proper rest. 2. Sleep in a proper position turning to your left side, use pillow one in between the legs and one under your abdomen or there are C shaped pregnancy pillow available. 3. Keep your back straight while walking and sitting. 4. Gently massage your back. ( Take help from others for massage) 5. Using hot water bag at the back will also help the pain to reduce. For lower abdominal pain to reduce, drink plenty of oral fluids eat lots of vegetables and fruits, take 10 mins brisk walk after dinner, don t refrain yourself from going to look as it might cause UTI. Coming to your pain in the breast, applying evening prime rose oil is sometimes helpful for some patients. Hope the above answers are helpful for you. Take care.