Hello, My husband has been dealing with pain and swelling in his arms and hand, even up into his shoulders since the beginning of August. He had blood work to rule out RA with an RF study, ANA screen/titer, hepatitis C antibody, c-reactive protein, sed rate, uric acid and basic blood work and they showed negative for RA, lupus or gout. But it they did show an increase in inflammatory markers. He has taken Prednisone and Relafen which didn t help at all. He is in constant pain and is cold all the time. He finally got an appointment with an RA doctor because his current physician took all this time to get it done but its still a week away and I m worried something is becoming seriously wrong.