I have been experiencing pressure and fullness in my lower abdomen for about 1-1/2 weeks. I care for a child who is now quite 2, so I usually do a lot of liftimg without any discomfort. I am also experiencing diarrhea. I have been very stressed .. Living with my daughter and grandson who is going through a divorce. It definitely feels better when I rest it and I have even applied a cold pack which really helped. I m 58 years old, female, had a colonoscopy last year that was perfectly clear, and I m in good health. I take .125 mg synthroid, 50 mg Zoloft, and 10 mg zocor daily along with 2000 mg omega 3 and a multivitamin daily. I don t have any discomfort today except the diarrhea.