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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Prolonged Vaginal Spotting And Cramping While On Letrozole?

I took letrozole on day 3 of my period for 5 days. 3 days after my period suppose to end im still spotting and cramping. Is this normal. I do have irregular periods and initially took provera to bring it on. Should i contact my doctor or will the spotting eventually stop to try and conceive?
Thu, 30 Apr 2020
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General Surgeon,  's  Response
Hello,

* As per my clinical experience, the Femara ( Letrozole ) is a very well known anti estrogen drug used for cancer breast patients , usually post menopausal period.

* Usually the patient is having ERPR positive breast lesion for whom this therapy is prescribed, and as there is anti estrogen drug, there can be alterations at Hypothalmus pituitary axis.

* The bleeding uterus is a major threat of use of Letrozole and this period is not ideal for making conceive issue positively. However, kindly discuss the issue with your doc regarding the same.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr. Bhagyesh V. Patel
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What Causes Prolonged Vaginal Spotting And Cramping While On Letrozole?

Hello, * As per my clinical experience, the Femara ( Letrozole ) is a very well known anti estrogen drug used for cancer breast patients , usually post menopausal period. * Usually the patient is having ERPR positive breast lesion for whom this therapy is prescribed, and as there is anti estrogen drug, there can be alterations at Hypothalmus pituitary axis. * The bleeding uterus is a major threat of use of Letrozole and this period is not ideal for making conceive issue positively. However, kindly discuss the issue with your doc regarding the same. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr. Bhagyesh V. Patel