I have severe breakout sessions mainly at night. Down my back and both arms. However, I can spread it anywhere if I scratch any part of my body. It can happen anytime of day, but mainly at night. I went to a dermatologist 2 years ago and she just told me I have high levels of histamine and put me on allergy meds. It doesnt happen during the summer months, just the winter. major hives, itchy, red, and my skin feels like burning.