Can you name an illness that mimics pyruvate carboxylase deficiency in terms of symptoms (minus mental developmental delays)? My 2-year old and 4-year old are both sick -- seizures, lethargy, fatigue. The 2-year old also has physical developmental delay, hypotonia, abnormal urinary odor, hypoglycemia and unformed stools. At one point the 2-year olds lab results showed elevated pyruvate. The 4-year old also has skin rash and alopecia and at one point had low thyroid function. No diagnosis to date.