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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Severe Confusion While On High Depakote Dosage?

My depakote was recently increased from 750mgs to 2000mgs per day so that my levels were good after blood work. For 3 weeks I ran out of medication and before I got another prescription I drank... ( which i shouldn t be and don t because i m in recovery but without my medication I feel the need to unfortunately) I just signed up for outpatient therapy but the night before i did my fiance woke me up and i had no idea where I was, i couldn t count to ten, he recorded all of it and i couldn t watch. Was it the increase of depakote that gave me the reaction or was it my drinking? I don t plan on drinking ever again. Depakote is the first med after many years that has actually helped with my bipolar disorder after abusing opiates for many years. Should I be mindful of what i m taking? This medication is scaring me. Can you please give me some facts on this medication?
Wed, 23 May 2018
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General & Family Physician 's  Response
Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.

The confusion and irrelevant episode counts to combined effects of over dose of sodium valproate along with exacerbation via alcohol intake.

Hope this clarifies your doubt.

Thanks

Dr Purva
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What Causes Severe Confusion While On High Depakote Dosage?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. The confusion and irrelevant episode counts to combined effects of over dose of sodium valproate along with exacerbation via alcohol intake. Hope this clarifies your doubt. Thanks Dr Purva