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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Severe Muscle And Joints Pain While Taking Prozac For Depression?

for the last 8 weeks i have been having muscle and joint pain..now getting more severe to the point at times i can hardly get out of bed,on occasion i awake from sleep crying in pain.i have been diagnosed with depression for 20 years and never had pain like this .i have been on proxac for my depression for 16 years,i cant figure out where this pain is coming from,the only relief i get is when i take acedominiphine with codine( 2) 800 mgs
Tue, 15 Nov 2022
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Anesthesiologist 's  Response
Hello,

The following may be few probable causes of pain in muscles and joints.
1) Rheumatoid arthritis
2) Osteoarthritis
3) Reactive arthritis
4) Polymyalgia rheumatica
5) Septic arthritis
6) Gout
7) Psoriatic arthritis
To arrive at a specific diagnosis, you need to take the following tests:
1) Complete blood picture
2) ESR
3) CRP
4) RA factor
5) Vitamin D levels

You can take the following treatment till you consult a rheumatologist or orthopedic surgeon:
1) NSAIDs like Ibuprofen or Aceclofenac daily 2 for 10 days
2) If you have cardiac disease you have to avoid the above medication
3) To prevent gastric irritation, tab. Pantoprazole 40 mg is to be taken once daily before food
4) Tab. Prednisolone 10 mg once daily for 10 days. Then 5 mg for 5 days and 5 mg alternate days for 3 days
5) Opioids like Hydrocodone, Oxycodone and Tramadol can also be taken
Please do consult a rheumatologist as soon as possible.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Pallavi M., Anesthesiologist
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General & Family Physician Dr. Dr. Nupur K's  Response
Hello,

You are suffering from pain and have history of depression. You have been taking Proxac for depression for a long period. Any medicine taken for a long period can cause side effects. You are suggested to get clinically examined by your treating doctor or GP, get a complete medical check up done.

You will have to get all required blood tests, investigations and imaging tests done to detect the pathology causing you pain and discomfort, you will be accordingly treated. Musculoskeletal side effects of the medicine you have been taking are muscle twitching, arthralgia, leg cramps, bone pain, arthritis, myalgia, osteoporosis, back pain, etc.

You are advised to report your symptoms to your treating doctor so that the medicine can be replaced with some other medicine that will suit you better. Get any chronic disease detected treated as early as it can so that you get relieved of the symptoms that cause you discomfort.

You are suggested to get connected to a Physical therapist so that your symptoms can be treated with therapies like talk therapy, massage therapy, cognitive behavioral therapy, etc. Do regular walking, exercises and take home made healthy fresh balanced food. Avoid any kind of anxiety and stress (emotional and physical), avoid addictions if any, do not smoke, do not take alcohol / drugs, etc.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Nupur K., General & Family Physician
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What Causes Severe Muscle And Joints Pain While Taking Prozac For Depression?

Hello, The following may be few probable causes of pain in muscles and joints. 1) Rheumatoid arthritis 2) Osteoarthritis 3) Reactive arthritis 4) Polymyalgia rheumatica 5) Septic arthritis 6) Gout 7) Psoriatic arthritis To arrive at a specific diagnosis, you need to take the following tests: 1) Complete blood picture 2) ESR 3) CRP 4) RA factor 5) Vitamin D levels You can take the following treatment till you consult a rheumatologist or orthopedic surgeon: 1) NSAIDs like Ibuprofen or Aceclofenac daily 2 for 10 days 2) If you have cardiac disease you have to avoid the above medication 3) To prevent gastric irritation, tab. Pantoprazole 40 mg is to be taken once daily before food 4) Tab. Prednisolone 10 mg once daily for 10 days. Then 5 mg for 5 days and 5 mg alternate days for 3 days 5) Opioids like Hydrocodone, Oxycodone and Tramadol can also be taken Please do consult a rheumatologist as soon as possible. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Pallavi M., Anesthesiologist