Hello, my name is Brittany. My mother is currently being treated to figure out what could be causing some sever pain in her hip to her knee. She has a build up knot in her knee. She has had this knot removed before. We do not know what could be causing this knot. She has had a MRI and X-rays on her knee, hip, and back. Everything came back to be fine. I was wondering if you know of any medication that may cause her bones to become brittle. She has taken the medication Paxil, Neurontin, Xanax, Wellbutrin, Tramadal, Clonidine, Zoloft, Premarin, Trazadone, and Lithium. Cancer also runs in our family. Could this be a possible solution.