The arthralgias associated with cymbalta us... What is the distribution of joints involved? I have moderately severe right wrist pain........but no other joint pain issues. No redness, heat or swelling of the right wrist. And no history of trauma or any new history of new repetitive movements for my right hand. I do have multiple myeloma...and from chemo, have developed severe neuropathies ...stocking, glove distribution...hence the script for cymbalta.