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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Sleeplessness And Rapid Heart Rate While On Prednisone?

I received an injection of Depo-Medrol last Tuesday and was prescribed oral Prednisone for 9 days after that for an allergic reaction to yellow fly bites. I have been having trouble sleeping, feeling that my heart is beating harder than normal, and feeling very anxious at night. I took 3 20-mg tablets for 2 days, then 2 20-mg tablets for 2 days, and then stopped because of the way I was feeling. Are these side effects from the Prednisone and how long will it take to get out of my system.?
Wed, 29 Aug 2018
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General & Family Physician,  's  Response
Hi,

Use of steroids systematically can affect the cardiovascular system and the nervous system by causing the symptoms you explain like sleeplessness, anxiety and the changes in the heartbeat.The effect of a single injection of Depo Medrol may last an average of two weeks so it is expected that your symptoms may last for around this time period but should be getting better with time.

If you notice you are not improving but you are getting any worse then you will need to talk with your doctor.

Hope I have answered your query.
Let me know if I can assist you further.
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What Causes Sleeplessness And Rapid Heart Rate While On Prednisone?

Hi, Use of steroids systematically can affect the cardiovascular system and the nervous system by causing the symptoms you explain like sleeplessness, anxiety and the changes in the heartbeat.The effect of a single injection of Depo Medrol may last an average of two weeks so it is expected that your symptoms may last for around this time period but should be getting better with time. If you notice you are not improving but you are getting any worse then you will need to talk with your doctor. Hope I have answered your query. Let me know if I can assist you further.