What causes sludge in the bile duct (gallbladder removed 2003) & what is the best way to treat it? I I have had pancreatitis two times as a result of attempt to place plastic stent in bile duct. I have mast cell release syndrome and wasn t on the correct dose of steroid pre op. The next time the plastic stent was placed without issue, sludge was removed & lasted 8 months before 100% blockage. Had stent replaced without incident but within a week the pain, nausea etc returned. They went it the stent was 100% occluded again. So, it was decided to not replace the stent and go into a wait and see mode. Unfortunately, I am experiencing increased pain, contraction type feeling in the area of the bile duct and am unable to eat many foods. I was already following the FOD MAP diet and I should also note that I have a pancreatic divisum which was found at the time of the first pancreatitis. Where do I go from here? permanent stent? And what if mast cell release syndrome causes this same issue - flares the mast cell and stent has to be removed