I took Bactrim and D Mannose after dinner, in the middle of the night I woke up with my arms feeling like they were swollen and very painful after looking at my arms they were not swollen but the muscles in my arms felt like they were gone and very heavy and painful i had to keep them still or it was worse. my face was also pale. I also just felt very strange. My doctor wants me to start taking the Bactrim after 24hrs and start the D Mannose the next day if all goes well. I am reluctant to take either. don t know what I should do.