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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Swelling In The Throat And Tongue After Taking Enalapril?

My husband just got out of hospital as he had a reaction (throat swelling and tongue swelling) to enalopril He has been on this for over 10 years. However he is on Chemo affinitor pills as well since may 2016 The doctor at Methodist hospital, San Antonio, Tx, took him off Enalapril and now prescribed Cozaar. (which is the HCTZ of enalapril) so pharmacy, today sept 1, 2016, says no one can tell you if it is enalapril or HCTZ that does the swelling so they said no to his Cozarr after contacting his dr, and told him to get new blood pressure medicine from his primary Dr which it is Labor day weekend. Is there a safe blood pressure medicine of a different family of these that do one cause swelling of the tongue and throat? Is that true no one knows if its enalapril or HCTZ which specific ingredient that causes the swelling?
Tue, 27 Sep 2016
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General & Family Physician,  's  Response
Hi
Thank you for asking HCM.
I have gone through your query. Enalapril is well known for its side effect angioedema in small percent of people. So it should be the most likely offender. Cozaar (losartan) is much more tolerated. Hctz usually doesn't give such side effect. You can follow your doctor's present advise. But if the discomfort exist then you should have a review again or go to ER.

Hope this may help you. Let me know if anything not clear.
Thanks.
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What Causes Swelling In The Throat And Tongue After Taking Enalapril?

Hi Thank you for asking HCM. I have gone through your query. Enalapril is well known for its side effect angioedema in small percent of people. So it should be the most likely offender. Cozaar (losartan) is much more tolerated. Hctz usually doesn t give such side effect. You can follow your doctor s present advise. But if the discomfort exist then you should have a review again or go to ER. Hope this may help you. Let me know if anything not clear. Thanks.