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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Terrible Hangovers After Drinking Alcohol?

After a night of drinking I experience terrible hang overs. They are considerably worse than anyone I have ever met. If I drink 5 or more drinks at one setting, even if it is over a long period of time, I will still get a hangover. My typical hangover consists of vomiting even without eating. I will not be able to eat or drink anything, even water, until it has psssed. The vomiting seems to be triggered when I am not laying down. If I lay down,the urge to vomit is not as prevalent. The hangover can last until 4pm - 11 pm or later, depending how much alcohol I consumed.I am curious why my hangover is considerably worse than anyone I know and why I am not able to put anything into my body the next day without vomiting?
Mon, 29 Dec 2014
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Addiction Medicine Specialist 's  Response
Over 4 drinks is considered risky behavior both in the short term and often indicating a drinking problem. Furthermore, "more problems than anyone I know" is an indicator of a drinking problem. AND most concerning is that still drinking when one has bad effects from it, is a definition of addiction.
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Then, several factors can contribute to having more hangovers than other people. Being smaller and/or female will result in more alcohol level than other people. A small but significant number of caucasians have a genetic low level of the liver enzyme that gets rid of alcohol and higher levels build up. Probably the majority of Asians lack a different enzyme that breaks down the alcohol biproduct acetaldehyde that causes some of the nausea associated with alcohol. Dehydration from any source increases hangover and rehydration helps it.
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What Causes Terrible Hangovers After Drinking Alcohol?

Over 4 drinks is considered risky behavior both in the short term and often indicating a drinking problem. Furthermore, more problems than anyone I know is an indicator of a drinking problem. AND most concerning is that still drinking when one has bad effects from it, is a definition of addiction. . Then, several factors can contribute to having more hangovers than other people. Being smaller and/or female will result in more alcohol level than other people. A small but significant number of caucasians have a genetic low level of the liver enzyme that gets rid of alcohol and higher levels build up. Probably the majority of Asians lack a different enzyme that breaks down the alcohol biproduct acetaldehyde that causes some of the nausea associated with alcohol. Dehydration from any source increases hangover and rehydration helps it.