Hello, I understand your concern for tiredness along with sensitive painful skin. It appears from your query that you have some internal systemic issue along with the skin issues. You have not mentioned in your age, sex and occupation along with nay other systemic complaints and relevant history and since how long you have the tiredness along with sensitive painful skin. In your kind of cases I prefer to go for systemic examination along with complete blood examination including hemoglobin, liver function test and kidney function test to rule out any internal related issues. Most of the times your kind of symptoms are associated with low level of hemoglobin and just correction of hemoglobin along with iron content is sufficient to treat all the conditions. In my patients with your kind of problem I prefer to give iron therapy along with good diet to have earliest recovery. All the best.