Unexplained weight gain of over 40 lbs. in 6 months. Trying to lose weight (was successful losing approx. 35 lbs. the previous year) weight started returning even though watching what eating, even used a personal trainer for 2 months with NO results. legs swollen (very hard, can put a dent pushing with pressure) have been to endocrinologist, rheumatologist, etc., etc. nothing definitive, a few tests slightly off, a lot of joint pain. Have had lyme disease more than once, titers came back negative. Have a heart murmer and on meds for ventricular tachachardia.