Hi Donepezil can cause nausea and vomiting as one of it s common side effects. I would suggest my patients to begin donepezil at low doses to avoid this effect. Beginning at 5 mg may be helpful in your case. I would suggest you to consult your doctor before deciding on stopping the drug. As discussed cutting down the dose is an option or medications can be given to prevent vomiting or alternative drugs can be considered. I hope the above information helps you. Thanks for writing into healthcaremagic. Have a nice day.