Thank you but I think I have found the answer to my question. I was in terrible pain in my left shoulder. the doctor prescribed Narprosyn (500 mg and Flexeril. After taking this combination at hs I began throwing up and a stingy discomfort in my mouth. for three nights, so I have stopped taking both. Because I m hypertensive, etc. I am no longer in pain and hope that it last. I had taken both meds for a week and two days. I hope that I will remain pain free. I am 77 years young, very active, good look in and want to remain the same. Thanks.