Hi Mark, your questions and symptoms indeed are varied and seem unrelated. Can you tell me a little more about your grandson, how old he is, any other pertinent medical problems? A routine blood test with chemistry panel is a good place to start, assuming these were already done. Has he had an endoscopy or colonoscopy, ultrasound of the abdomen or CT scan of the abdomen? These are all imaging modalities I would consider in addition to the kidney scan, which I am curious, what prompted that line of thinking? It is true that hypertension is commonly due to kidney issues but it wouldn t be the first place I would start. Perhaps by kidney scan you mean a CT scan of the abdomen. Other thoughts include celiac disease, lactose intolerance, among other intestinal malabsorption conditions. I have many questions for your grandson: Where does he live? Any recent foreign travel? Any pertinent family history? Has he had any abnormalities on lab test performed to date, such as anemia? Was he fine prior to 4 months ago? Why did he see an endocrinologist? Many of the answers to these questions can help elucidate the etiology of your grandsons condition, but a formal consultation with a pediatric gastroenterologist would be my next recommendation if the renal scan came out normal. Please report back.