I have gained 9 lbs in 2 weeks, (edema) what could it be? I was on a water pill called triamterine and I still had swelling, so after at least a yr, I started on spirolactone. My lower bp numer has been over 110. so bp is running 140/110. I was started on metepherolol 25. I have NEVER gained ten lbs in 2 weeks, but it is true. I have RA and fibromyalgia, and the extra weight is NOT helping me.