My wife is on Norvasc 5mg, Epilim 600mg, Galvus Met 50/500mg, Concor 2.5mg and Diamicron 120mg. From my initial research all but Concor causes weight gain. We have watched our diet , reduced unnecessary calorie intake all to no avail. The weight continues to increase. Since being diagnosed with Bipolar Disorder 20 years ago her weight has increased from 125 to 240 pounds. Our doctors, while admitting to some extent that meds are contributing to the weight, gain are not being proactive beyond giving advice on portion sizes. What options do we have?