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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Could Positive Sjogrens Antibody, In The Test Report Suggest?

Hi there- I just came home from my Rheumatologist visit and received blood work results that I want to make sure I understand. My Dr. told me that 2 tests showed positive for Lupus but we would retest in November. Under the results section- the anti-nuclear antibodies came back- POSITIVE (NEGATIVE) A Sjogrens SS-A Antibody- came back- 508 RNP ANTIOBODY- 171 What are your thoughts on this?
Thu, 4 Sep 2014
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Pathologist and Microbiologist,  's  Response
Hi!
welcome to HCM!
The antinuclear antibody (ANA) test is used as a primary test to help evaluate a person for autoimmune disorders and is most often used as one of the tests to help diagnose systemic lupus erythematosus (SLE).
SS-A/Ro antibodies occur in patients with several different connective tissue diseases including Sjogren syndrome, lupus erythematosus (LE) (40%-60% of cases); and rheumatoid arthritis. SS-A/Ro antibodies are associated with childhood LE and with features of extraglandular inflammation in patients with LE including vasculitis, purpura, cytopenias, and adenopathy.
Antibodies to RNP occur in approximately 50% of patients with lupus erythematosus (LE) .
Your results are in favour of SLE.
Hope this helps!
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What Could Positive Sjogrens Antibody, In The Test Report Suggest?

Hi! welcome to HCM! The antinuclear antibody (ANA) test is used as a primary test to help evaluate a person for autoimmune disorders and is most often used as one of the tests to help diagnose systemic lupus erythematosus (SLE). SS-A/Ro antibodies occur in patients with several different connective tissue diseases including Sjogren syndrome, lupus erythematosus (LE) (40%-60% of cases); and rheumatoid arthritis. SS-A/Ro antibodies are associated with childhood LE and with features of extraglandular inflammation in patients with LE including vasculitis, purpura, cytopenias, and adenopathy. Antibodies to RNP occur in approximately 50% of patients with lupus erythematosus (LE) . Your results are in favour of SLE. Hope this helps!