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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Do ASO, CRP, VDRL, Widle And Brucella Tests Detect?

hi i am a student in the laboratory . can any doctor write for me about ASO test(what is the diseases of it and some informrmation about it) , CRP , VDRL ,widle and brucella . i want the answer now please.
Sat, 30 Jun 2012
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Pathologist and Microbiologist 's  Response
hello. Welcome to HCM.
Your query regarding tests:
1. ASO titre indicates Anti streptolysin O which is used to detect present or recent infection with Streptococcus bacteria. Clinically, the test is important because this infection can be associated with Rheumatic Fever and be complicated by Valvular heart disease in future life. Its interpretation varies from lab to lab, if qualitative test, agglutination is observed.
2. CRP: is a non-specific but commonly ordered test, a high level of which indicates inflammation- mostly severe bacterial but also immune disorders.A significant level is generally above 1.0 mg/dl
3. Widal Test: Is the test done for testing typhoid. Widal tests titres of antibody against O, and H antigens mainly. There is a qualitative, semiquantitative and quantitative Widal Test. a titre above 1 in 160 is considered significant.
4. Brucella: Exact diagnosis depends on demonstation of organism, which is slow to grow and carries risk of infection to personnel. There are few tests like MiLK RING test/ Rose Bengal Test etc.Or an appropriate clinical picture along with granulomas in liver.
Hope this helps.
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What Do ASO, CRP, VDRL, Widle And Brucella Tests Detect?

hello. Welcome to HCM. Your query regarding tests: 1. ASO titre indicates Anti streptolysin O which is used to detect present or recent infection with Streptococcus bacteria. Clinically, the test is important because this infection can be associated with Rheumatic Fever and be complicated by Valvular heart disease in future life. Its interpretation varies from lab to lab, if qualitative test, agglutination is observed. 2. CRP: is a non-specific but commonly ordered test, a high level of which indicates inflammation- mostly severe bacterial but also immune disorders.A significant level is generally above 1.0 mg/dl 3. Widal Test: Is the test done for testing typhoid. Widal tests titres of antibody against O, and H antigens mainly. There is a qualitative, semiquantitative and quantitative Widal Test. a titre above 1 in 160 is considered significant. 4. Brucella: Exact diagnosis depends on demonstation of organism, which is slow to grow and carries risk of infection to personnel. There are few tests like MiLK RING test/ Rose Bengal Test etc.Or an appropriate clinical picture along with granulomas in liver. Hope this helps.