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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Do The Titer Results Of 1:8 For Syphilis Indicate?

How can someone syphilis titer go from 1:1 to 1:8 within a yr? what does this mean? My doctor says I had to be reinfected, but I m married and I really don t believe my husband stepped out on me. Could this be flare up from my last infection? I don t know because my doctor said if it was it wouldn t go up that high pass 1:4 being it went up to 1:8 is cause for concern. Please help me better understand this whole thing. Thank You God bless
Tue, 21 Jul 2015
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General & Family Physician,  's  Response
Hello,
I want to know whether you are diagnosed case or the titre you have given is of screening test.
RPR AND VDRL ARE used for screening or for quantitation of the serum antibody.
Titre reflects disease activity rising during the evolution of early syphilis and often exceeding 1:32 in secondary syphilis.
Adequate response to treatment is indicated by persistent fall by two dilutions or more after treatment.
Titers less than 1:8 may be reactive and in such cases autoimmune conditions and injection drug use should be ruled out.
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What Do The Titer Results Of 1:8 For Syphilis Indicate?

Hello, I want to know whether you are diagnosed case or the titre you have given is of screening test. RPR AND VDRL ARE used for screening or for quantitation of the serum antibody. Titre reflects disease activity rising during the evolution of early syphilis and often exceeding 1:32 in secondary syphilis. Adequate response to treatment is indicated by persistent fall by two dilutions or more after treatment. Titers less than 1:8 may be reactive and in such cases autoimmune conditions and injection drug use should be ruled out.