Hello, The report is indicative of over burden of the plaque most likely due to: - Hypercholesterolemia - Obesity - Diabetes - Smoking - Other reasons There is nothing to panic for, but various therapeutic modalities with life style modifications do help a great to make the things smoother as: - Control of body weight - Control of blood sugar and cholesterol - Regular aerobics, walking, swimming and routine activities - Anti lipid therapy with atorvastatin or rosuvastatin - Anti platelet drugs as clopidrogel or others - Quit smoking if applicable - Diet control to avoid all spices, non veg, dairy fat, junk items Regular follow up with your cardiologist is best way to keep yourself fit and fine. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Bhagyesh V. Patel, General Surgeon