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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does this liver Test Result Mean?

i had been vaccinated in childhood for hepatitus b , and before complete 3 doses of vaccination, my status was hbsag non reactive, while i was 2 years old, now i am 24, just from some routine blood tests, my reports read that i am hbsag reactive. liver function test are normal except sgot= 38 and sgpt= 55, liver fibroscan (elasticity measurement-liver stiffness value is 5.3 kpa). hepatitis B e antibody is reactive with value 0.010 hepatitus B e antigen is non reactive with value of 0.31. qualitative HBV DNA Reports are awaited….. what is the current status of my infection, is it acute or chronic ?? how is it possible vaccine dint work for me and now i am hbsag reactive ?? can the reports be wrong ?? i am very much worried……please explain
Mon, 11 Feb 2019
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General & Family Physician,  's  Response
Hi,

Interpretation of Hep B tests are complex. But let's make it easy in your case.

1. Presence of HBs Ag mean that the person is infected with the virus. However it does not tell about weather it's chronic or acute. It depends on checking the results, if it's positive for more then 6 months then it's chronic if less then 6 months then it's acute. Another way of checking it is to check for anti-HBc antibodies, IgG mean chronic, IgM positive mean acute. In your case it can't be said as we don't have the tests in hand.

2. Regarding immunity by the vaccine, you are right, vaccine offer protection but it's not always the case. So, for this reason, we check the status by checking the anti-HBs antibodies level after completing the course to see if vaccination was successful. Even if successful it may not give life long protection and need to be checked every five to 10 years.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Mahboob Ur Rahman, General & Family Physician
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What Does this liver Test Result Mean?

Hi, Interpretation of Hep B tests are complex. But let s make it easy in your case. 1. Presence of HBs Ag mean that the person is infected with the virus. However it does not tell about weather it s chronic or acute. It depends on checking the results, if it s positive for more then 6 months then it s chronic if less then 6 months then it s acute. Another way of checking it is to check for anti-HBc antibodies, IgG mean chronic, IgM positive mean acute. In your case it can t be said as we don t have the tests in hand. 2. Regarding immunity by the vaccine, you are right, vaccine offer protection but it s not always the case. So, for this reason, we check the status by checking the anti-HBs antibodies level after completing the course to see if vaccination was successful. Even if successful it may not give life long protection and need to be checked every five to 10 years. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Mahboob Ur Rahman, General & Family Physician