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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does PSA Test Reading 42 Indicate?

My husband was diagnosed with prostate cancer 6 years ago and has been on Zoladex and Casadex ever since. These were no longer doing the job and his PSA started rising to 11 in June 2010. So he had a bone scan and Pelvic MRI which showed no spread. He then had 19 doses of Radiotherapy. After 6 weeks he had a PSA test which has come back at 42.
This seems very high to us, is this normal. What reading should we expect after Radiotherapy
Tue, 2 Jun 2015
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Pulmonologist,  's  Response
Thanks for your question on Health Care Magic.
I can understand your concern.
PSA (prostate specific antigen) is marker for prostate cancer. And it's value correlates with activity of cancer.
High PSA level suggests higher tumour burden.
And after radiotherapy, PSA level should be decreased.
But in his case, it's value is increased. It suggests that tumour is not responding to radiotherapy.
In my opinion, he should undergo PET scan to rule out local tumour size and distant metastasis.
So better to consult oncologist and discuss all these.
Hope I have solved your query.
Wishing good health to your husband.
Thanks.
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What Does PSA Test Reading 42 Indicate?

Thanks for your question on Health Care Magic. I can understand your concern. PSA (prostate specific antigen) is marker for prostate cancer. And it s value correlates with activity of cancer. High PSA level suggests higher tumour burden. And after radiotherapy, PSA level should be decreased. But in his case, it s value is increased. It suggests that tumour is not responding to radiotherapy. In my opinion, he should undergo PET scan to rule out local tumour size and distant metastasis. So better to consult oncologist and discuss all these. Hope I have solved your query. Wishing good health to your husband. Thanks.