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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does A High T3 Uptake Mean In A Thyroid Test?

I had a thyroid test yesterday, and the guy giving me the results said I need to talk to a doctor about them.

The results were:

T3 Uptake: 46% (High)
Thyroxine (F4) 7.2
Free Thyroxine Index 3.3
TSH 1.13

What does a high T3 uptake mean? Do I need to get something prescribed? I'm male by the way.
Wed, 12 Apr 2017
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General & Family Physician,  's  Response
Hi & Welcome.

Incomplete data like age, purpose of doing these tests, any associated symptoms ???

T3-Uptake test measures the amount of thyroxine-binding globulin (TBG) in the serum. When TBG is decreased, T3 uptake is increased, and vice versa.
This is an indirect measure of thyroid hormone levels. It has nothing to do with T3, despite the name and it does not measure the level of T3 or T4 in serum.

Increased levels are found in hyperthyroidism, lung disease and certain cancers.

Free T4 is the most accurate assessment of thyroid hormone levels, because it avoids changes in plasma protein binding capabilities.

You are advised to consult an endocrinologist/physician for further clinical evaluation and possible anti-thyroid medications.
Hope this answers your query.
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What Does A High T3 Uptake Mean In A Thyroid Test?

Hi & Welcome. Incomplete data like age, purpose of doing these tests, any associated symptoms ??? T3-Uptake test measures the amount of thyroxine-binding globulin (TBG) in the serum. When TBG is decreased, T3 uptake is increased, and vice versa. This is an indirect measure of thyroid hormone levels. It has nothing to do with T3, despite the name and it does not measure the level of T3 or T4 in serum. Increased levels are found in hyperthyroidism, lung disease and certain cancers. Free T4 is the most accurate assessment of thyroid hormone levels, because it avoids changes in plasma protein binding capabilities. You are advised to consult an endocrinologist/physician for further clinical evaluation and possible anti-thyroid medications. Hope this answers your query.