hi. noted history of liver lesion on imaging study. is your wife experiencing any abdominal symptoms (like pain, fullness, nausea, vomiting) or systemic symptoms (like weight loss, fever, fatigue)? does she have any history of hepatitis or other types of liver infection? it is best if you tell your wife to consult with a doctor, preferably a general surgeon or a gastroenterologist, for physical examination and clinical evaluation. benign vs malignant tumor lesions must be ruled out. one important thing to rule-out is hepatocellular carcinoma. other diagnostics (such as ct-scan if not yet done, liver function tests, bilirubins, tumor markers, blood count, etc.) and management (medical and/or surgical if indications are found) will be directed accordingly. hope this helps. good day!! ~dr.kaye