Hello, Thank you for your query. Any headaches that is unusual or not relieved with the usual medications needs to evaluated by a doctor through detailed physical examination. * how old are you? male or female * do you have any other medical issues or take any medications? * do you have prescription glasses? have you checked the power recently? * do you have any other symptoms like fever, headache, nausea, vomiting? * if you throw up, does it relieve your headache? * any sinusitis, cold? * how is your urine and stools? I recommend: - a physician consult - an ophthalmologist consult - ct scan of the brain , if clinically indicated - blood tests (complete blood count) - Cerebrospinal fluid analysis , if required increased intracranial pressure, eye trouble, sinusitis can all cause unrelenting headaches. certain migraines can present like this too. Please see your doctor asap, Hope this helps. Wish you good health