Hi, Thanks for using healthcaremagic. Deep white matter infarction and chronic ischemic changes are same. It occurs due to blockage of microvasculature and small infarctions of the white matter of brain. These do not cause severe problems/symptoms and can be ignored. Gliosis in both frontal lobes are a result of some previous insult. He must have had some previous hemorrhage/stroke or some surgical procedure which causes this gliosis. This can cause some symptoms as well. Small white matter lesion can also be ignored. The major finding is the gliosis which is a result of old insult. So nothing much to worry right now in the brain MRI. You can contact me for further queries if any. Hope it sorts your problem. Regards, Dr. Pankaj Nagori Specialist Radiology