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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does The Platelet Level Of 45000 And Creatine 150-180 Suggest?

My creatine level has been 150 - 180 for over 18months without any treatment. I am 80 yrs and have aortic valve replacement and removal of spleen due to low plateles at around 45000. Now settled at 160 - 180. with 5 mg prednisolone.. Am also on nebilet 2,5mg for bp control at Have had blood tests for INR since 1985 (0n warfarin). Also creatinine measured but no tretment ever suggested. So appears this kidney level has remained stable for years. How do I rate ? Dennis
Mon, 7 Aug 2017
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Nephrologist 's  Response
Dear Dennis,

you have a decreased renal function, that may be the expression of the aortic valve replacement (increased the risk of cholesterol embolism) and the splenectomy (risk of AKI). Since you are 80 year old, kidneys have a very limited functional reserve. Thus, any clinical condition, like dehydration, may rise sharply your serum creatinine. Thus, be sure to be followed by a good nephrologist and make sure that your physician do not prescribe you nephrotoxic drugs. Avoid NSAIDS, control your blood pressure, limit the salt intake to less than 2 g/day. Moreover, ask your doctor to perform a urinalysis, since renal inflammation (e.g. glomerulonephritis) are frequently observed in older age.
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What Does The Platelet Level Of 45000 And Creatine 150-180 Suggest?

Dear Dennis, you have a decreased renal function, that may be the expression of the aortic valve replacement (increased the risk of cholesterol embolism) and the splenectomy (risk of AKI). Since you are 80 year old, kidneys have a very limited functional reserve. Thus, any clinical condition, like dehydration, may rise sharply your serum creatinine. Thus, be sure to be followed by a good nephrologist and make sure that your physician do not prescribe you nephrotoxic drugs. Avoid NSAIDS, control your blood pressure, limit the salt intake to less than 2 g/day. Moreover, ask your doctor to perform a urinalysis, since renal inflammation (e.g. glomerulonephritis) are frequently observed in older age.