Hi, Thanks for posting in HCM. I understand your concern. GGT level with 385 is more than 6 times higher than normal. It is mainly increased in alcoholic liver disease. It is an inducible enzyme which gets elevated in chronic alcoholics. Based on the history, it is very much evident that your husband liver function has been badly damaged and gone in to the stage of cirrhosis (fibrosis). Conservative line of management may be tried by use of medications, but might not be that useful in the long run. He may probably need to undergo liver transplant at some stage during the course of treatment. Kindly consult Gastroenterologist with the report for clinical evaluation and appropriate management. Hope the information provided would be helpful. All the best.