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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does This Report Signify And Is It Enough Matched To Undergo A Transplant Operation For CKD Patient (stage V) ?

I am a CKD (stage V) patient and now on Hemodialysis since jan,2011. My height is 5 5 , dry Weight 50 kg. My age is 22. I Want to transplant. Here is the report of HLA tissue test and cross match report. I want to mention that doner is the sister of my mother. HLA Tissue Type: Patient: DRB1 : 04,07. Other than DRB1 : DRB4. A Locus : 68,_. B Locus : 44,55. C Locus : 1,_. Others : BW4,BW6. Doner: DRB1 : 07,15. Other than DRB1 : DRB4. A Locus : 1,34. B Locus : 13,44. C Locus : 3,_. Others : BW4,BW6. Cross Match Report: T cell cross match: at 4 degree centigrade : 10%. at 37 degree centigrade : 10%. B cell cross match: at 4 degree centigrade : 5%. at 37 degree centigrade : 15%. What does this report signify and is it enough match to undergo a transplant operation ?
Sat, 18 Jun 2011
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Nephrologist 's  Response
You have a less than perfect match. If you do not have any other donor,You can still go ahead with transplantation but with the use of an induction agent like Anti thymocytic globulin and higher immunosuppression. You will have an increased risk of graft rejection than others with a better match.
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What Does This Report Signify And Is It Enough Matched To Undergo A Transplant Operation For CKD Patient (stage V) ?

You have a less than perfect match. If you do not have any other donor,You can still go ahead with transplantation but with the use of an induction agent like Anti thymocytic globulin and higher immunosuppression. You will have an increased risk of graft rejection than others with a better match.