Hi dear, I had gone through your question and understand your concerns. Dear, I want to know more about you like whats your age and do have any other chronic illness.. Have you taken any medication for any other reason.. Normally, if you don t have any medical issue then there is nothing change in your hormones after having intercourse or loose virginity.. Only 1 thing that if you will get pregnancy with that then there is lots of hormonal changes started but if you had safe protected sex then there is no change at all.. Only emotionally you can feel changes in both way - you ll be more happy and may be you have pain after loose virginity but that is not permanent... but i want to know more about your history.. But normally there is no change.. Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. I will be happy to answer your questions. Wishing you good health. Regards Dr Neeraj Garg MD, DM Endocrinologist SPS Hospitals Ludhiana, Punjab