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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Is HLA-B27 Test And Why Is It Suggested?

Hello Dr,

My husband is having a back pain. We have gone through some tests (CRP,ESR, RA factor ,uric acid and HLA-B27, cytometry. Got report of some only one which is HLA-B27 is remaining. XRAY and MRI is normal.
Could you please let me know what is HLA-B27 test and why it is suggested? is there any chances of cancer?
Below are the current report details:
ESR : 30mm
CRP: 20.80
ra factot: >10
uric acid : 7.30
HLA-B27: report awaiting

thanks you for information
Tue, 11 Aug 2015
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Radiologist,  's  Response
Hello

Your husband's findings may suggests raised ESR,uric acid and CRP level.
Raised ESR and CRP may indicate infection/inflammation in the body.
It need clinical correlation and it may be due to arthritis.

HLA-B27 estimation is also related to arthritis and it is a blood test for a protein that is found on the surface of WBC.
Positive HLA-B27 may be present in ankylosing spondylitis,psoriatic arthritis,reactive arthritis etc.
Your husband may need specific medicines for arthritis after clinical estimation.

Findings are not related to cancer.Don't worry about this.

Get well soon.
Take Care
Dr.Indu Bhushan
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What Is HLA-B27 Test And Why Is It Suggested?

Hello Your husband s findings may suggests raised ESR,uric acid and CRP level. Raised ESR and CRP may indicate infection/inflammation in the body. It need clinical correlation and it may be due to arthritis. HLA-B27 estimation is also related to arthritis and it is a blood test for a protein that is found on the surface of WBC. Positive HLA-B27 may be present in ankylosing spondylitis,psoriatic arthritis,reactive arthritis etc. Your husband may need specific medicines for arthritis after clinical estimation. Findings are not related to cancer.Don t worry about this. Get well soon. Take Care Dr.Indu Bhushan