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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Is Arthus Reaction And What Is Its Incubation Period?

What is arthus reaction, how long would it take for symptons to occur and how long would they last. I am 32, 121lbs, had my splen removed at 15, had 1 pnemonia shot, then again at 25. But recenlty had a 3rd, my doctor said that Arthus reaction would be the only rare concern. However i had the shot two days ago and the area is red, sore to touch and slightly swollen.
Thu, 12 Mar 2015
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Infectious Diseases Specialist 's  Response
Hello there,
I am dr.milan an infectious disease specialist answering your question.
Arthus reactions have been infrequently reported after vaccinations containing diphtheria and tetanus toxoid and few other including pneumococcal.
Arthus reactions is a hypersensitivity reactions are rarely reported after vaccination. An Arthus reaction is a local inflammation of blood vessels associated with deposition of immune complexes and activation of complement, body's immune response. Immune complexes form at the site of high local concentration of vaccine antigens and high circulating antibody concentration.
Arthus reactions are characterized by severe pain, swelling, induration, edema, hemorrhage, and occasionally by necrosis. These symptoms and signs usually occur 4–12 hours after vaccination. Recommendation is that persons who experienced an Arthus reaction after a dose of vaccine should not receive vaccine more frequently.
I feel this is not arthus reaction. And you should follow advise of your treating physician.
Hope i have given appropriate guidance to you.
if you have any query you can consult me anytime.
Give me star rating, helpful vote & thank you according to your satisfaction level.
Thanking you.
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What Is Arthus Reaction And What Is Its Incubation Period?

Hello there, I am dr.milan an infectious disease specialist answering your question. Arthus reactions have been infrequently reported after vaccinations containing diphtheria and tetanus toxoid and few other including pneumococcal. Arthus reactions is a hypersensitivity reactions are rarely reported after vaccination. An Arthus reaction is a local inflammation of blood vessels associated with deposition of immune complexes and activation of complement, body s immune response. Immune complexes form at the site of high local concentration of vaccine antigens and high circulating antibody concentration. Arthus reactions are characterized by severe pain, swelling, induration, edema, hemorrhage, and occasionally by necrosis. These symptoms and signs usually occur 4–12 hours after vaccination. Recommendation is that persons who experienced an Arthus reaction after a dose of vaccine should not receive vaccine more frequently. I feel this is not arthus reaction. And you should follow advise of your treating physician. Hope i have given appropriate guidance to you. if you have any query you can consult me anytime. Give me star rating, helpful vote & thank you according to your satisfaction level. Thanking you.