Hi, Aside from the bone marrow, which is traditionally considered a source for stem cells, we may find stem cells in the periphery.The stem cell program at the Texas Heart Institute is focused primarily on treating heart failure, be it related to a recent myocardial infarction or a chronic disease state. There s a lot of effort to understand all the effects of these different cell types, including the potential mechanisms of action- 1)One of the proposed mechanisms of cellular therapy is angiogenesis; the idea that bone marrow cells may be able to secrete multiple potentially angiogenic substances as well as transdifferentiate into cells that create new blood vessels is fairly well established in pre-clinical studies. 2)myogenesis, which is a little bit more controversial, especially when we talk about transdifferentiation of bone-marrow-derived cells into heart muscle cells. We know that there may be dedicated precursors of cardiomyocytes in the myocardium. We are still trying to determine if the transplanted cells themselves differentiate, or if paracrine effects from the transplanted cells stimulate stem cells already resident in the heart to differentiate. Hi but these things are still under reserch and long term trials are still awaited. i would suggest you to go for a left ventricular assisted device before heart transplantation.Its much more succesful.