It appears that your mother is suffering from Frailty. It is a clinical condition caused by chronic illness compounding physiological decline of old age. There is weight loss (loss of muscle mass), fatiguability, difficulty walking or even climbing a few steps, low level of activity and weak hand grip. Some general principles of treatment are: Treat her medical condition properly. Ensure proper nutrition. Proteins, calories and vitamins. Keep her active, keep her out of bed as much as possible. Social stimulation. Physiotherapy helps to build muscle strength and also gives much needed human contact. She can even do exercises while lying in bed or sitting in chair. I hope this answers your question.