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Most commonly these disorders are caused by abnormalities of minerals such as calcium, phosphorus, magnesium or vitamin D leading to dramatic clinical disorders that are commonly reversible once the underlying defect has been treated.
Osteomalacia and rickets
Vitamin D deficiency results in incomplete osteoid mineralisation
In childhood, prior to epiphyseal closure, causes rickets
In adults causes osteomalacia
Causes
Vitamin D deficiency
Malabsorption Post-gastrectomy or bowel resection Coeliac disease
Cirrhosis
Renal disease
Renal tubular disorder (e.g. familial hypophosphataemic rickets)
Chronic renal failure Anticonvulsant therapy
Tumours
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What Is The Cause, Symptoms And Treatment Of Metabolic Bone Disorder?
Usually it seen in cases of parathyroid disorders.