Hello This is Dr Adil Ramzan. Thank you for asking question. A high white blood cell count suggests an acute infection. I would also like to know the percentage of neutrophills and some other cells to have a better idea about the acute or chronic nature of infection. anyhow, high wbc count suggests that there is an ongoing infection inside your father s body. Having pus cells in urine, suggest there is urinary tract infection and usually the first drug that is periscribed in the absence of culture and sensitivity report is ciprofloxacin. Moreover, if your father s wbc count don t decrease within next 2 -3 days then you may consider shifting him to hospital for a course of injectable antibiotics such as ceftriaxone. Moreover, if culture report is negative but still there is fever and high wbc count then i would continue antibiotics and explore for any other source of infection my asking more questions and doing examination and also i may require few more investigations. for example a chest x-ray as you have told that your father is also suffering from cold. Kind regards. Dr Adil