Hello, metformin is a very useful drug for type 2 diabetes. Starting metformin requires a low dose at first (500mg per day is ok) to avoid gastrointestinal side effects. Also please take into account that most antidiabetic drugs require adequate renal function. If your renal function is OK and you don t have severe heart (or other organ) failure then you can use metformin. You can increase the dose after a couple of weeks too. And you can also use glimepiride if your blood sugar won t get under control with the onglyza-metformin regimen. Just remember to adjust the doses appropriately to avoid hypoglycemic episodes. I hope I ve helped! You can contact me again, if you d like more information or clarifications. Kind Regards!