Enatamoeba histolytica infection can be treated with some simple antibiotics which may be given in oral or intravenous form. Whether the child needs to be hospitalised depends on the hydration status. If there is dehydration, there is requirement of hospitalisation. But in case adequate ORS and fluids can be given orally, the option of treating at home with oral medication can be tried. However, if your pediatrician advises, hospitalisation may be a better idea as the gastrointestinal absorbtion of medicines might be a bit erratic in children of this age. The best thing depends upon your convenience and the actual situation.