Hello, You are on the right and good molecule for treating depression ( taking that the diagnosis is right!!). You have not provided with the symptom details of the illness, your mood etc, which is a limitation in making a diagnosis. There is a dictum which we follow in psychiatry treatment- when the suitable drug dosent give response: we revise the diagnosis by again attending the patient in detail and see if something is missed due to which the drugs are not working. However, you may ask the doctor to try a.different molecule - like venalafaxine ( a better molecule than escitalopram) and see if it helps. For nausea and weight gain- you will feel good and light by taking an antacid ( pantoperazole) emptyvstomach. and make soem.life style.changes- running, jym, or brisk walk, cut down sugary and oily foods to reduce wieght. Remember, drus only increase appetite but weight gain depends on what you eat or what you put in your mouth...so, get a control on what you eat and no drug of psychiatry managment can make you fat. Hope the reply helps you Dr. Manisha Gopal MD Psychiatry