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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Which Drug Is Less Cardio Toxic For Heart Disease?

I have stage 1 IDC breast cancer with a double mastectomy and nnuclear node mapping. 6 sentinel nodes were benign. However my grade is 2/3 with positive Er Pr and positive her2. I have afib and heart disease. Herceptin and kadcyla are box labels for cardio toxicity as well as tykerb can cause prolong qt. I am in 1st degree heart block. Which drug is less cardio toxic
Sat, 12 Apr 2014
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Cardiologist 's  Response
Dear patient,

Cardiotoxicity from all those breast cancer agents is similar, and unfortunately difficult to predict. A fib or first degree heart block however would not be contraindications for treatment with those. You will need a baseline Echocardiogram with strain imaging and regular follow up after chemo with Echo.

Hope this helps, wish you the best,

Dr Brenes-Salazar MD
Mayo Clinic MN
Cardiology
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Which Drug Is Less Cardio Toxic For Heart Disease?

Dear patient, Cardiotoxicity from all those breast cancer agents is similar, and unfortunately difficult to predict. A fib or first degree heart block however would not be contraindications for treatment with those. You will need a baseline Echocardiogram with strain imaging and regular follow up after chemo with Echo. Hope this helps, wish you the best, Dr Brenes-Salazar MD Mayo Clinic MN Cardiology